A new dimeric protoberberine alkaloid and other compounds from the tubers of Tinospora dentata

Sio Hong Lam, Shu Duan Jian, Tsong Long Hwang, Po Jen Chen, Hsin Yi Hung, Ping Chung Kuo, Tian Shung Wu

研究成果: Article同行評審

摘要

A new dimeric quaternary protoberberine alkaloid, bispalmatrubine (1), and thirteen known compounds (2-14) were purified from the tubers of Tinospora dentata. Their structures were determined by spectroscopic and spectrometric analytical methods. Among the isolates, eight compounds were examined for their in vitro anti-inflammatory potential and several tested alkaloids displayed moderate inhibitory effects of N-formyl-methionyl-leucyl-phenylalanine/cytochalasin B (fMLP/CB)-induced superoxide anion generation and elastase release.

原文English
頁(從 - 到)17-24
頁數8
期刊Natural Product Research
35
發行號1
DOIs
出版狀態Published - 2021

All Science Journal Classification (ASJC) codes

  • 分析化學
  • 生物化學
  • 植物科學
  • 有機化學

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