A portable platform for the quantification of Vitamin D levels by using paper-based microfluidic

Chen Hsun Weng; Hsin Yi Chou; Ming Huang Chen; Yu-Sheng Lin

doi:10.1109/BMEiCON.2018.8609988

A portable platform for the quantification of Vitamin D levels by using paper-based microfluidic

Chen Hsun Weng, Hsin Yi Chou, Ming Huang Chen, Yu-Sheng Lin

研究成果: Conference contribution

6 引文斯高帕斯（Scopus）

摘要

Vitamin D deficiency has been linked to several diseases and adverse outcomes including: diabetes, cardiovascular diseases, and even cancer. At present the clear majority of vitamin D testing is performed in large-scale laboratories at the request of a physician as part of an annual panel of blood tests. Here we present a paper-based microfluidic system for rapid quantification of vitamin D levels on a portable platform. The system consists of a smartphone accessory, an app, and a test strip that allows the colorimetric detection of 25-hydroxyvitamin D using a novel gold nanoparticle-based immunoassay. We show that the system can be used to accurately measure physiological levels of 25-hydroxyvitamin D with accuracy better than 25 nM and a precision of 10 nM. We compare our system with well-established ELISA test kits for serum samples of unknown concentration and demonstrate equivalency of the results.

原文	English
主出版物標題	BMEiCON 2018 - 11th Biomedical Engineering International Conference
發行者	Institute of Electrical and Electronics Engineers Inc.
ISBN（電子）	9781538657249
DOIs	https://doi.org/10.1109/BMEiCON.2018.8609988
出版狀態	Published - 2019 1月 10
事件	11th Biomedical Engineering International Conference, BMEiCON 2018 - Chaing Mai, Thailand 持續時間: 2018 11月 21 → 2018 11月 24

出版系列

名字	BMEiCON 2018 - 11th Biomedical Engineering International Conference

Conference

Conference	11th Biomedical Engineering International Conference, BMEiCON 2018
國家/地區	Thailand
城市	Chaing Mai
期間	18-11-21 → 18-11-24

All Science Journal Classification (ASJC) codes

人工智慧
生物醫學工程
儀器

UN SDG

此研究成果有助於以下永續發展目標

存取文件

10.1109/BMEiCON.2018.8609988

其它文件與鏈接

引用此

Weng, C. H., Chou, H. Y., Chen, M. H., & Lin, Y.-S. (2019). A portable platform for the quantification of Vitamin D levels by using paper-based microfluidic. 於 BMEiCON 2018 - 11th Biomedical Engineering International Conference 文章 8609988 (BMEiCON 2018 - 11th Biomedical Engineering International Conference). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/BMEiCON.2018.8609988

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title = "A portable platform for the quantification of Vitamin D levels by using paper-based microfluidic",

abstract = "Vitamin D deficiency has been linked to several diseases and adverse outcomes including: diabetes, cardiovascular diseases, and even cancer. At present the clear majority of vitamin D testing is performed in large-scale laboratories at the request of a physician as part of an annual panel of blood tests. Here we present a paper-based microfluidic system for rapid quantification of vitamin D levels on a portable platform. The system consists of a smartphone accessory, an app, and a test strip that allows the colorimetric detection of 25-hydroxyvitamin D using a novel gold nanoparticle-based immunoassay. We show that the system can be used to accurately measure physiological levels of 25-hydroxyvitamin D with accuracy better than 25 nM and a precision of 10 nM. We compare our system with well-established ELISA test kits for serum samples of unknown concentration and demonstrate equivalency of the results.",

author = "Weng, {Chen Hsun} and Chou, {Hsin Yi} and Chen, {Ming Huang} and Yu-Sheng Lin",

note = "Publisher Copyright: {\textcopyright} 2018 IEEE.; 11th Biomedical Engineering International Conference, BMEiCON 2018 ; Conference date: 21-11-2018 Through 24-11-2018",

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Weng, CH, Chou, HY, Chen, MH & Lin, Y-S 2019, A portable platform for the quantification of Vitamin D levels by using paper-based microfluidic. 於 BMEiCON 2018 - 11th Biomedical Engineering International Conference., 8609988, BMEiCON 2018 - 11th Biomedical Engineering International Conference, Institute of Electrical and Electronics Engineers Inc., 11th Biomedical Engineering International Conference, BMEiCON 2018, Chaing Mai, Thailand, 18-11-21. https://doi.org/10.1109/BMEiCON.2018.8609988

A portable platform for the quantification of Vitamin D levels by using paper-based microfluidic. / Weng, Chen Hsun; Chou, Hsin Yi; Chen, Ming Huang 等.
BMEiCON 2018 - 11th Biomedical Engineering International Conference. Institute of Electrical and Electronics Engineers Inc., 2019. 8609988 (BMEiCON 2018 - 11th Biomedical Engineering International Conference).

研究成果: Conference contribution

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AU - Weng, Chen Hsun

AU - Chou, Hsin Yi

AU - Chen, Ming Huang

AU - Lin, Yu-Sheng

PY - 2019/1/10

Y1 - 2019/1/10

N2 - Vitamin D deficiency has been linked to several diseases and adverse outcomes including: diabetes, cardiovascular diseases, and even cancer. At present the clear majority of vitamin D testing is performed in large-scale laboratories at the request of a physician as part of an annual panel of blood tests. Here we present a paper-based microfluidic system for rapid quantification of vitamin D levels on a portable platform. The system consists of a smartphone accessory, an app, and a test strip that allows the colorimetric detection of 25-hydroxyvitamin D using a novel gold nanoparticle-based immunoassay. We show that the system can be used to accurately measure physiological levels of 25-hydroxyvitamin D with accuracy better than 25 nM and a precision of 10 nM. We compare our system with well-established ELISA test kits for serum samples of unknown concentration and demonstrate equivalency of the results.

AB - Vitamin D deficiency has been linked to several diseases and adverse outcomes including: diabetes, cardiovascular diseases, and even cancer. At present the clear majority of vitamin D testing is performed in large-scale laboratories at the request of a physician as part of an annual panel of blood tests. Here we present a paper-based microfluidic system for rapid quantification of vitamin D levels on a portable platform. The system consists of a smartphone accessory, an app, and a test strip that allows the colorimetric detection of 25-hydroxyvitamin D using a novel gold nanoparticle-based immunoassay. We show that the system can be used to accurately measure physiological levels of 25-hydroxyvitamin D with accuracy better than 25 nM and a precision of 10 nM. We compare our system with well-established ELISA test kits for serum samples of unknown concentration and demonstrate equivalency of the results.

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M3 - Conference contribution

AN - SCOPUS:85062055809

T3 - BMEiCON 2018 - 11th Biomedical Engineering International Conference

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PB - Institute of Electrical and Electronics Engineers Inc.

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Weng CH, Chou HY, Chen MH, Lin YS. A portable platform for the quantification of Vitamin D levels by using paper-based microfluidic. 於 BMEiCON 2018 - 11th Biomedical Engineering International Conference. Institute of Electrical and Electronics Engineers Inc. 2019. 8609988. (BMEiCON 2018 - 11th Biomedical Engineering International Conference). doi: 10.1109/BMEiCON.2018.8609988

A portable platform for the quantification of Vitamin D levels by using paper-based microfluidic

摘要

出版系列

Conference

All Science Journal Classification (ASJC) codes

UN SDG

存取文件

其它文件與鏈接

指紋

引用此