A portable platform for the quantification of Vitamin D levels by using paper-based microfluidic

Chen Hsun Weng, Hsin Yi Chou, Ming Huang Chen, Yu-Sheng Lin

研究成果: Conference contribution

3 引文 斯高帕斯(Scopus)

摘要

Vitamin D deficiency has been linked to several diseases and adverse outcomes including: diabetes, cardiovascular diseases, and even cancer. At present the clear majority of vitamin D testing is performed in large-scale laboratories at the request of a physician as part of an annual panel of blood tests. Here we present a paper-based microfluidic system for rapid quantification of vitamin D levels on a portable platform. The system consists of a smartphone accessory, an app, and a test strip that allows the colorimetric detection of 25-hydroxyvitamin D using a novel gold nanoparticle-based immunoassay. We show that the system can be used to accurately measure physiological levels of 25-hydroxyvitamin D with accuracy better than 25 nM and a precision of 10 nM. We compare our system with well-established ELISA test kits for serum samples of unknown concentration and demonstrate equivalency of the results.

原文English
主出版物標題BMEiCON 2018 - 11th Biomedical Engineering International Conference
發行者Institute of Electrical and Electronics Engineers Inc.
ISBN(電子)9781538657249
DOIs
出版狀態Published - 2019 1月 10
事件11th Biomedical Engineering International Conference, BMEiCON 2018 - Chaing Mai, Thailand
持續時間: 2018 11月 212018 11月 24

出版系列

名字BMEiCON 2018 - 11th Biomedical Engineering International Conference

Conference

Conference11th Biomedical Engineering International Conference, BMEiCON 2018
國家/地區Thailand
城市Chaing Mai
期間18-11-2118-11-24

All Science Journal Classification (ASJC) codes

  • 人工智慧
  • 生物醫學工程
  • 儀器

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