A simple electrokinetic protein preconcentrator utilizing nano-interstices

Yu Hung Chen, Hsuan Franziska Wu, Tamara G. Amstislavskaya, Chang Yu Li, Chun Ping Jen

研究成果: Article同行評審

12 引文 斯高帕斯(Scopus)

摘要

This work proposes a simple method for creating nanofluidic channels for protein preconcentration through self-assembled gold nanoparticles (AuNPs) using the exclusion-enrichment effect. A depletion force is elicited in nano-interstices among self-assembled AuNPs due to the overlap of electrical double layers (EDLs); therefore, proteins quickly accumulate. The experimental results show that the generation of depletion forces is correlated with the size of the AuNPs. The self-assembled monolayer of AuNPs (13 nm in diameter) can successfully preconcentrate proteins through effective EDL overlapping. This approach provides a new process to produce nanochannels that does not require high-voltage or time-consuming fabrication.

原文English
文章編號024121
期刊Biomicrofluidics
10
發行號2
DOIs
出版狀態Published - 2016 3月 1

All Science Journal Classification (ASJC) codes

  • 生物醫學工程
  • 材料科學(全部)
  • 凝聚態物理學
  • 流體流動和轉移過程
  • 膠體和表面化學

指紋

深入研究「A simple electrokinetic protein preconcentrator utilizing nano-interstices」主題。共同形成了獨特的指紋。

引用此