This study aims to evaluate the course of disaster nursing through assessing nursing students’ satisfaction, knowledge and skills gain and impact on practices by the Kirkpatrick’s evaluation model. Seventy undergraduate nursing students were surveyed. The study adopted the Kirkpatrick’s evaluation model which contains four levels. Data were presented by descriptive statistics, Person correlation and t-test to conduct the analysis. Level 1 “Reaction”, the significant positively correlation existed between course satisfaction and teaching strategies. Level 2 “Learning”, post-test data was significantly higher than pre-test data. There was positively significant correlation existed between level 3 (Behavior) and level 4 (Result). Our course programs can be used as a reference for future nursing schools offer related courses to prepare the implementation of disaster nursing courses and teaching methods, establish suitable disaster nursing education programs for our national conditions.