It is quite difficult to investigate thermal comfort in hot–humid regions, and there have not been many real case studies or research related to this issue. In this article, four running events held in nearby popular travel spots in Kaohsiung, the largest city in southern Taiwan, were selected to analyze the influence of thermal environment and air quality on thermal comfort. Mostly real time environmental monitoring data were applied for estimating thermal indicators, along with Sky View Factor (SVF) data taken at the sites of the running scheduled routes, to analyze the thermal performance of participants at running events. Compared with runners, walkers (local residents, fans, and staff of the events) would be exposed to a greater risk of thermal discomfort with increasing time spent on the routes. With the integrated analysis, mPET (modified physiologically equivalent temperature) can be viewed as a relatively comprehensive indicator in considering both environmental thermal conditions and the biometrical differences of activities and clothing types. From the results, a good correlation between mPET and solar radiation/SVF was obtained, which indicated that mPET could be sufficiently sensible in revealing the thermal condition variation from one site to another during the route with time. Based on the discomfort risk assessment, for runners, the event held in autumn with lower SVF at the route sites would be less risky of thermal discomfort, while the event held in spring with lower solar radiation would be more comfortable for walkers. As for air quality condition, the inappropriateness of holding winter outdoor activities in Kaohsiung was obviously shown in both real time monitoring data and long term analysis.
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