Adult methicillin-resistant Staphylococcus aureus bacteremia in Taiwan: clinical significance of non-multi-resistant antibiogram and Panton-Valentine leukocidin gene

Jiun Ling Wang, Jann Tay Wang, Shey Ying Chen, Po Ren Hsueh, Hsiang Chi Kung, Yee Chun Chen, Shan Chwen Chang

研究成果: Article同行評審

12 引文 斯高帕斯(Scopus)

摘要

It is poorly defined whether or not adult patients with methicillin-resistant Staphylococcus aureus (MRSA) bacteremia with a non-multi-resistant antibiogram phenotype and Panton-Valentine leukocidin (PVL) gene carriage have different clinical syndromes. Clinical characteristics of 95 adult patients of MRSA bacteremia, with isolates that were non-multi-resistant to non-β-lactam, were compared with a contemporaneous multiresistant group. Independent risk factors other than community-associated MRSA bacteremia patients associated with recovery of non-multi-resistant MRSA isolates by multivariate analysis included deep-seated infection and catheter insertion site infection. Older age, intensive care unit-onset bacteremia, and postoperative infection were negative independent risk factors associated with non-multi-resistant MRSA isolates. Most of the 60 recoverable non-multi-resistant MRSA isolates belonged to multilocus sequence type 59, and all isolates belonged to staphylococcal chromosomal cassette mec (SCCmec) element type IV or type V. Most PVL-positive MRSA isolates belonged to SCCmec V. PVL-positive CA-MRSA isolates could cause more deep-seated infections in patients presented with non-multi-resistant MRSA bacteremia.

原文English
頁(從 - 到)365-371
頁數7
期刊Diagnostic Microbiology and Infectious Disease
59
發行號4
DOIs
出版狀態Published - 2007 十二月

All Science Journal Classification (ASJC) codes

  • Microbiology (medical)
  • Infectious Diseases

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