An electro-microchip for immunoassay using gold nanoparticle and silver enhancement

Keng Shiang Huang, Hao Hsuan Huang, Tsung Chain Chang, Hong Ping Lin, Yung Chiang Chung, Yu Cheng Lin

研究成果: Paper同行評審

1 引文 斯高帕斯(Scopus)

摘要

This paper reports a novel immunoassay using an electro-microchip to detect the immuno-reaction signal and the silver enhancement reaction to magnify the detection signal. Moreover, gold nanoparticles (ANPs) play the roles of a label for antigen or antibody and a catalyst for silver precipitation. The change of the impedance to corroborate immuno-reaction is detected, amplified and analyzed. The results show that using the gap size of 20 μm electro-chip has the best sensitivity. The relationship between concentration and signal is established and the antigen detection limit is 100 ng/mL.

原文English
頁面305-307
頁數3
出版狀態Published - 2006 一月 1
事件10th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2006 - Tokyo, Japan
持續時間: 2006 十一月 52006 十一月 9

Other

Other10th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2006
國家Japan
城市Tokyo
期間06-11-0506-11-09

All Science Journal Classification (ASJC) codes

  • Chemical Engineering (miscellaneous)
  • Bioengineering

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