An immunoassay using platinum nanoparticles, silver enhancement and a electrodes chips

Kuei Ling Su, I. Long Wang, Po Yu Tu, Yung Chiang Chung, Yu-Cheng Lin

研究成果: Conference contribution

摘要

This paper reports a novel immunoassay using an electro-microchip to detect the immuno-reaction signal and the silver enhancement reaction to magnify the detection signal. Moreover, platinum nanoparticles (PtNPs) play the roles of a label for antigen or antibody and a catalyst for silver precipitation. The change of the impedance to corroborate immuno-reaction is detected, amplified and analyzed. The developed method shows that a chip with a 50 μm length 150 μm electrodes gap size has the highest sensitivity. Therefore, using an electro-microchip, antibody-PtNPs conjugates and a silver enhancement reaction, a new immunoassay is successfully constructed.

原文English
主出版物標題Proceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences
發行者Chemical and Biological Microsystems Society
頁面1008-1011
頁數4
ISBN(列印)9780979806421
出版狀態Published - 2009 一月 1
事件13th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2009 - Jeju, Korea, Republic of
持續時間: 2009 十一月 12009 十一月 5

出版系列

名字Proceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences

Other

Other13th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2009
國家/地區Korea, Republic of
城市Jeju
期間09-11-0109-11-05

All Science Journal Classification (ASJC) codes

  • 化學工程(雜項)
  • 生物工程

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