An integrated microfluidic system for continuous selection of aptamers by using tissue samples

Wei Ting Liu, Wen Bin Lee, Yi Cheng Tsai, Lien Yu Hung, Chien Yu Fu, Yuan Jhe Chuang, Keng Fu Hsu, Gwo Bin Lee

研究成果: Conference contribution

摘要

In this work, an integrated microfluidic system was presented to select specific aptamers by performing a tissue-based systematic evolution of ligands by exponential enrichment (Tissue-SELEX) in a continuous format. Ovarian cancer tissue slides were used as the target to screen the cancer-specific aptamers. This system was consisted of a flow control module, a temperature control module and an integrated microfluidic chip. The Tissue-SELEX processes could be automatically carried out on the developed microfluidic system.

原文English
主出版物標題21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017
發行者Chemical and Biological Microsystems Society
頁面1435-1436
頁數2
ISBN(電子)9780692941836
出版狀態Published - 2020 一月 1
事件21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017 - Savannah, United States
持續時間: 2017 十月 222017 十月 26

出版系列

名字21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017

Conference

Conference21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017
國家United States
城市Savannah
期間17-10-2217-10-26

All Science Journal Classification (ASJC) codes

  • Chemical Engineering (miscellaneous)
  • Bioengineering

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  • 引用此

    Liu, W. T., Lee, W. B., Tsai, Y. C., Hung, L. Y., Fu, C. Y., Chuang, Y. J., Hsu, K. F., & Lee, G. B. (2020). An integrated microfluidic system for continuous selection of aptamers by using tissue samples. 於 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017 (頁 1435-1436). (21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017). Chemical and Biological Microsystems Society.