An integrated selex microfluidic system for rapid screening of influenza virus-specific aptamers

Hsien Chih Lai, Chih Hung Wang, Chen-Hsun Weng, Tong Miin Liou, Gwo Bin Lee

研究成果: Conference contribution

2 引文 斯高帕斯(Scopus)

摘要

An integrated microfluidic system was developed to automatically perform systematic evolution of ligands and exponential enrichment (SELEX) process using combinational single-stranded DNA (ssDNA) library for rapid screening of highly specific aptamers for influenza viruses in this study. This integrated microfluidic system consisted of several modules on a single chip. With this system, the specific aptamers were screened successfully with high affinity for influenza viruses after several repeated extraction and amplification runs. Therefore, it may provide a useful platform for specific aptamers screening, which can be a promising biomarker to recognize viruses for fast diagnosis.

原文English
主出版物標題Proceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012
發行者Chemical and Biological Microsystems Society
頁面1402-1404
頁數3
ISBN(列印)9780979806452
出版狀態Published - 2012 一月 1
事件16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012 - Okinawa, Japan
持續時間: 2012 十月 282012 十一月 1

出版系列

名字Proceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012

Other

Other16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012
國家Japan
城市Okinawa
期間12-10-2812-11-01

All Science Journal Classification (ASJC) codes

  • Chemical Engineering (miscellaneous)
  • Bioengineering

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