Ankle–Brachial Index Predicts Long‐Term Renal Outcomes in Acute Stroke Patients

研究成果: Article同行評審


Renal dysfunction is common after stroke. We aimed to investigate the clinical predictability of the ankle–brachial index (ABI) and brachial‐ankle pulse wave velocity (baPWV) on post-stroke renal deterioration. A total of 956 consecutive participants with acute ischemic stroke between 1 July 2016, and 31 December 2017 were enrolled and a final of 637 patients were recruited for final analysis. By using the group‐based trajectory model (GBTM), the patients’ renal function trajectories were grouped into the low, intermediate, and high categories (LC, IC, and HC). Significant deterioration in the slope was noted in the IC (p < 0.001) and LC (p = 0.002) groups but was nonsignificant in the HC (p = 0.998) group. Abnormal ABI (ABI ≤ 0.9) was independently related to LC (adjusted odds ratio: 2.40; 95% CI, 1.16–4.95; p = 0.019) and was also independently associated with increased risks of a ≥ 30% decline in eGFR (adjusted hazard ratio [aHR], 2.28; 95% CI, 1.29– 4.05; p = 0.005), a doubling of serum creatinine (aHR, 3.60; 95% CI, 1.93–8.34; p < 0.001) and ESRD (HR, 3.28; 95% CI, 1.23–8.74; p = 0.018). However, baPWV did not have a significant relationship with any of the renal outcomes. Patients with a lower ABI during acute stroke should receive regular renal function tests and should be closely monitored to improve poststroke renal care.

期刊Healthcare (Switzerland)
出版狀態Published - 2022 5月

All Science Journal Classification (ASJC) codes

  • 健康資訊學
  • 健康政策
  • 健康資訊管理
  • 領導和管理


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