Anti-cancer efficacy of dietary polyphenols is mediated through epigenetic modifications

Jia Ching Wu, Ching Shu Lai, Pei Sheng Lee, Chi Tang Ho, Wen Shiung Liou, Ying Jan Wang, Min Hsiung Pan

研究成果: Review article同行評審

12 引文 斯高帕斯(Scopus)


Accumulating studies in tumorigenesis indicate that dysregulated gene expression caused by genetic and epigenetic changes lead to the formation of human cancers, and most dysregulated or dysfunctional genes are associated with cell proliferation, programmed cell death (PCD), metastasis, and, in part, tumor suppressor genes (TSGs) or oncogenes. Epigenetic modifications are important regulatory mechanisms that are induced by chemical treatment or environmental changes. Recently, studies have considered the effects of epigenetic modifications on tumorigenesis and disease. Over the past few decades, dietary polyphenols have become a focus of investigation because of their bioactive function in cancer prevention and treatment. In this review article, we summarize the current research on the anti-cancer effects of polyphenols and provide useful information to help promote polyphenol application in cancer research.

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期刊Current Opinion in Food Science
出版狀態Published - 2016 4月 1

All Science Journal Classification (ASJC) codes

  • 食品科學
  • 應用微生物與生物技術


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