Antibiotic susceptibility test based on the dielectrophoretic behavior of elongated Escherichia coli with cephalexin treatment

Cheng Che Chung, I. Fang Cheng, Wen-Horng Yang, Hsien-Chang Chang

研究成果: Article

15 引文 (Scopus)

摘要

This study reports the use of dielectrophoresis (DEP), which determined the crossover frequency (cof) of antibiotic-induced elongation of Escherichia coli (E. coli) with regard to the rapid antibiotic susceptibility test (AST). Different dielectric properties and elongation rates of E. coli are caused by various concentrations of cephalexin treatment. According to the authors' results, significant changes in the cof of bacteria treated with 32 μg/ml antibiotic for 60 min can be found by using a quadruple electrode array, and the results of DEP-based AST correspond with that of agar dilution method. Utilizing this approach could greatly reduce the period of bacteria growth, and obtain the minimum inhibition concentration of E. coli to cephalexin.

原文English
文章編號021102
期刊Biomicrofluidics
5
發行號2
DOIs
出版狀態Published - 2011 一月 1

指紋

Cephalexin
antibiotics
Antibiotics
Escherichia
Escherichia coli
Anti-Bacterial Agents
magnetic permeability
Electrophoresis
bacteria
elongation
Elongation
Bacteria
crossovers
Dielectric properties
Dilution
Agar
dilution
dielectric properties
Electrodes
electrodes

All Science Journal Classification (ASJC) codes

  • Molecular Biology
  • Materials Science(all)
  • Genetics
  • Condensed Matter Physics
  • Physical and Theoretical Chemistry

引用此文

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