Virtual reality (VR), a computer-generated interactive environment, is provided to a user by projecting a peripheral image onto environmental surfaces. VR has an advantage of enhancing the immersive experience. Nowadays, VR has been widely applied in tourism and cultural experience. On the other hand, a recent integration of electroencephalography-based (EEG-based) brain-computer interface (BCI) and VR is capable of promoting the immersive virtual experience. Therefore, our study aims to propose an integrative framework to implement EEG-based BCI in a VR game to advance the cultural experience. A room escape game in a Tainan temple is created. EEG signals arc recorded while users arc playing the game. The online analyses of EEG signals arc used to interact with the VR display. This integrative framework can result in a better experience than the conventional setup.