Assessment of optical properties in cerebral ischemic rats by using near infrared spectroscopy

Wan Chen Shao, Chun Wei Wu, Chun Man Yuan, Jia Jin Jason Chen

研究成果: Conference contribution

摘要

Ischemic stroke is a high prevailing disease and costly in industrialized countries. A valid animal model is essential to develop an extensive research. Among various models, we choose middle cerebral artery occlusion (MCAO) model as it is one of the common used ischemic stroke animal models. The purpose of our study is to investigate the optical properties of ischemic stroke by near infrared spectroscopy (NIRS) with the wavelength in 830 and 690 nm. The optical properties include the absorption coefficient, reduced scattering coefficient and hemodynamic responses. It shows that the correlation between the reduced scattering coefficient and the brain infarction volume from histochemical stain is high in 830 nm, and moderate in 690 nm. Besides, there is significant difference in reduced scattering coefficient between infarction region at cortex and subcortex and that at subcortex only or sham group. These results show that NIRS can be an effective tool to evaluate ischemic stroke.

原文English
主出版物標題IECBES 2014, Conference Proceedings - 2014 IEEE Conference on Biomedical Engineering and Sciences
主出版物子標題"Miri, Where Engineering in Medicine and Biology and Humanity Meet"
發行者Institute of Electrical and Electronics Engineers Inc.
頁面807-810
頁數4
ISBN(電子)9781479940844
DOIs
出版狀態Published - 2014
事件3rd IEEE Conference on Biomedical Engineering and Sciences, IECBES 2014 - Kuala Lumpur, Malaysia
持續時間: 2014 十二月 82014 十二月 10

出版系列

名字IECBES 2014, Conference Proceedings - 2014 IEEE Conference on Biomedical Engineering and Sciences: "Miri, Where Engineering in Medicine and Biology and Humanity Meet"

Other

Other3rd IEEE Conference on Biomedical Engineering and Sciences, IECBES 2014
國家/地區Malaysia
城市Kuala Lumpur
期間14-12-0814-12-10

All Science Journal Classification (ASJC) codes

  • 生物醫學工程

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