Association of nonsynonymous substitutions in the intermediate region of the vacA gene of helicobacter pylori with gastric diseases in Taiwan

Shew Meei Sheu, Kuei Hsiang Hung, Bor Shyang Sheu, Hsiao Bai Yang, Jiunn Jong Wu

研究成果: Article同行評審

12 引文 斯高帕斯(Scopus)

摘要

The amino acid sequences corresponding to the vacA intermediate region from 39 isolates of Helicobacter pylori were investigated. The substitution of a G for the third S in the i1-type cluster B sequence (QASEGIT SSK) conferred a greater risk of gastric diseases (P < 0.03; Fisher's exact test). The conserved substitutions of an F for the Y in the cluster A sequence and of an M for the second N in the il-type cluster C sequence could be a marker of VacA in the Taiwanese strains.

原文English
頁(從 - 到)249-251
頁數3
期刊Journal of Clinical Microbiology
47
發行號1
DOIs
出版狀態Published - 2009 1月

All Science Journal Classification (ASJC) codes

  • 微生物學(醫學)

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