Association of the gamma-aminobutyric acid A receptor gene cluster with alcohol dependence in Taiwanese han

Y. T. Chang; H. S. Sun; C. S.J. Fann; C. J. Chang; Z. H. Liao; J. L. Huang; E. W. Loh; W. Y. Yu; A. T.A. Cheng

doi:10.1038/sj.mp.4001110

Association of the gamma-aminobutyric acid A receptor gene cluster with alcohol dependence in Taiwanese han

Y. T. Chang
, H. S. Sun
, C. S.J. Fann
, C. J. Chang
, Z. H. Liao
, J. L. Huang
, E. W. Loh
, W. Y. Yu
, A. T.A. Cheng

分子醫學研究所

研究成果: Article › 同行評審

13 引文斯高帕斯（Scopus）

摘要

In this study, five published single nucleotide polymorphisms in the GABA_A receptor gene cluster on 5q33-34, GABRB2 C1412T, GABRA6 C1236T and T1519C, GABRA1 A15G, and GABRG2 A123C were applied to examine the association between them and alcohol dependence with withdrawal symptoms among 158 cases and 149 controls in the Taiwanese Han. The GABRA6 T1519C polymorphism revealed a significant genotypic association (P=0.006).

原文	English
頁（從 - 到）	828-829
頁數	2
期刊	Molecular Psychiatry
卷	7
發行號	8
DOIs	https://doi.org/10.1038/sj.mp.4001110
出版狀態	Published - 2002

UN SDG

此研究成果有助於以下永續發展目標

SDG 3 良好的健康和福祉

All Science Journal Classification (ASJC) codes

分子生物學
精神病學和心理健康
細胞與分子神經科學

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10.1038/sj.mp.4001110

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title = "Association of the gamma-aminobutyric acid A receptor gene cluster with alcohol dependence in Taiwanese han",

abstract = "In this study, five published single nucleotide polymorphisms in the GABAA receptor gene cluster on 5q33-34, GABRB2 C1412T, GABRA6 C1236T and T1519C, GABRA1 A15G, and GABRG2 A123C were applied to examine the association between them and alcohol dependence with withdrawal symptoms among 158 cases and 149 controls in the Taiwanese Han. The GABRA6 T1519C polymorphism revealed a significant genotypic association (P=0.006).",

author = "Chang, \{Y. T.\} and Sun, \{H. S.\} and Fann, \{C. S.J.\} and Chang, \{C. J.\} and Liao, \{Z. H.\} and Huang, \{J. L.\} and Loh, \{E. W.\} and Yu, \{W. Y.\} and Cheng, \{A. T.A.\}",

year = "2002",

doi = "10.1038/sj.mp.4001110",

language = "English",

volume = "7",

pages = "828--829",

journal = "Molecular Psychiatry",

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TY - JOUR

T1 - Association of the gamma-aminobutyric acid A receptor gene cluster with alcohol dependence in Taiwanese han

AU - Chang, Y. T.

AU - Sun, H. S.

AU - Fann, C. S.J.

AU - Chang, C. J.

AU - Liao, Z. H.

AU - Huang, J. L.

AU - Loh, E. W.

AU - Yu, W. Y.

AU - Cheng, A. T.A.

PY - 2002

Y1 - 2002

N2 - In this study, five published single nucleotide polymorphisms in the GABAA receptor gene cluster on 5q33-34, GABRB2 C1412T, GABRA6 C1236T and T1519C, GABRA1 A15G, and GABRG2 A123C were applied to examine the association between them and alcohol dependence with withdrawal symptoms among 158 cases and 149 controls in the Taiwanese Han. The GABRA6 T1519C polymorphism revealed a significant genotypic association (P=0.006).

AB - In this study, five published single nucleotide polymorphisms in the GABAA receptor gene cluster on 5q33-34, GABRB2 C1412T, GABRA6 C1236T and T1519C, GABRA1 A15G, and GABRG2 A123C were applied to examine the association between them and alcohol dependence with withdrawal symptoms among 158 cases and 149 controls in the Taiwanese Han. The GABRA6 T1519C polymorphism revealed a significant genotypic association (P=0.006).

UR - https://www.scopus.com/pages/publications/0036382844

UR - https://www.scopus.com/pages/publications/0036382844#tab=citedBy

U2 - 10.1038/sj.mp.4001110

DO - 10.1038/sj.mp.4001110

M3 - Article

C2 - 12232773

AN - SCOPUS:0036382844

SN - 1359-4184

VL - 7

SP - 828

EP - 829

JO - Molecular Psychiatry

JF - Molecular Psychiatry

IS - 8

ER -

Association of the gamma-aminobutyric acid A receptor gene cluster with alcohol dependence in Taiwanese han

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