As₂O₃-induced c-Src/EGFR/ERK signaling is via Sp1 binding sites to stimulate p21^WAF1/CIP1 expression in human epidermoid carcinoma A431 cells

Keyphrases

• P21Cip1 100%
• C-Src 100%
• ERK Pathway 100%
• A431 Cells 100%
• Arsenic Trioxide 100%
• Sp1 Binding Site 100%
• Human Epidermoid Carcinoma 100%
• P21 Expression 83%
• Quantitative PCR 16%
• Apoptosis 16%
• Arsenic 16%
• Western Blotting 16%
• Cell Cycle Arrest 16%
• Site-directed mutagenesis 16%
• Reporter Assay 16%
• Acute Promyelocytic Leukemia 16%
• Cycloheximide 16%
• Gene Transcription 16%
• Src Activation 16%
• Cell Toxicity 16%
• Signaling Events 16%
• Post-transcriptional 16%
• Stabilization Mechanism 16%
• P21 Gene 16%
• Human Solid Tumors 16%
• Post-translational 16%

Pharmacology, Toxicology and Pharmaceutical Science

• Epidermal Growth Factor Receptor 100%
• Binding Site 100%
• Squamous Cell Carcinoma 100%
• Western Blot 33%
• Messenger RNA 33%
• Solid Malignant Neoplasm 33%
• Cytotoxicity 33%
• Site-Directed Mutagenesis 33%
• Promyelocytic Leukemia 33%
• Cycloheximide 33%

Biochemistry, Genetics and Molecular Biology

• Cell Mediated Cytotoxicity 14%