Autophagy facilitates an IFN-γ response and signal transduction

Yu Ping Chang, Chia Ling Chen, Su O. Chen, Yee Shin Lin, Cheng Chieh Tsai, Wei Ching Huang, Chi Yun Wang, Chia Yuan Hsieh, Pui Ching Choi, Chiou Feng Lin

研究成果: Short survey同行評審

11 引文 斯高帕斯(Scopus)

摘要

Autophagy, that is directly triggered by invaded pathogens and indirectly triggered by IFN-γ, acts as a defense by mediating intracellular microbial recognition and clearance. In addition, autophagy contributes to inflammation by facilitating an IFN-γ response and signal transduction. For immune escape, downregulated autophagy may be a strategy used by microbes.

原文English
頁(從 - 到)888-894
頁數7
期刊Microbes and Infection
13
發行號11
DOIs
出版狀態Published - 2011 十月 1

All Science Journal Classification (ASJC) codes

  • Microbiology
  • Immunology
  • Infectious Diseases

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