Bias of shear wave elasticity measurements in thin layer samples and a simple correction strategy

Jianqiang Mo, Hao Xu, Bo Qiang, Hugo Giambini, Randall Kinnick, Kai Nan An, Shigao Chen, Zongping Luo

研究成果: Article同行評審

15 引文 斯高帕斯(Scopus)

摘要

Shear wave elastography (SWE) is an emerging technique for measuring biological tissue stiffness. However, the application of SWE in thin layer tissues is limited by bias due to the influence of geometry on measured shear wave speed. In this study, we investigated the bias of Young’s modulus measured by SWE in thin layer gelatin–agar phantoms, and compared the result with finite element method and Lamb wave model simulation. The result indicated that the Young’s modulus measured by SWE decreased continuously when the sample thickness decreased, and this effect was more significant for smaller thickness. We proposed a new empirical formula which can conveniently correct the bias without the need of using complicated mathematical modeling. In summary, we confirmed the nonlinear relation between thickness and Young’s modulus measured by SWE in thin layer samples, and offered a simple and practical correction strategy which is convenient for clinicians to use.

原文English
文章編號1341
期刊SpringerPlus
5
發行號1
DOIs
出版狀態Published - 2016 12月 1

All Science Journal Classification (ASJC) codes

  • 多學科

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