Biomarker Discovery and Validation: Statistical Considerations

Fang Shu Ou, Stefan Michiels, Yu Shyr, Alex A. Adjei, Ann L. Oberg

研究成果: Article同行評審

摘要

Biomarkers have various applications including disease detection, diagnosis, prognosis, prediction of response to intervention, and disease monitoring. In this era of precision medicine, having validated biomarkers to inform clinical decision making is more important than ever. In this article, we discuss best the practices and potential issues in biomarker discovery and validation. We encourage team science partnerships to bring cutting-edge discovery from bench to bedside, leading to improved patient care and outcomes.

原文English
頁(從 - 到)537-545
頁數9
期刊Journal of Thoracic Oncology
16
發行號4
DOIs
出版狀態Published - 2021 四月

All Science Journal Classification (ASJC) codes

  • Oncology
  • Pulmonary and Respiratory Medicine

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