Biomimetic modification of the gliding surface of extrasynovial tendon

Yulong Sun, Chunfeng Zhao, Peter C. Amadio, Kai Nan An

研究成果: Article同行評審

2 引文 斯高帕斯(Scopus)

摘要

Tendons may be classified as intrasynovial or extrasynovial based upon their anatomic location. We studied the physical properties of extrasynovial and intrasynovial tendons. Extrasynovial tendon has a rougher surface and higher friction than intrasynovial tendon. A number of carbodiimide derivatized biomaterials were developed to modify the irregular surface of an extrasynovial tendon to mimic the smooth surface of an intrasynovial tendon. We found that carbodiimide derivatized hyaluronic acid-gelatin (cd-HA-gelatin) chemically bonded to the extrasynovial tendon surface and optimally reduced gliding resistance in vitro. This biosynthetic, biomimetic modification of the extrasynovial tendon surface may prove to be a useful clinical product.

原文English
頁(從 - 到)2079-2083
頁數5
期刊Journal of Materials Research
21
發行號8
DOIs
出版狀態Published - 2006 八月

All Science Journal Classification (ASJC) codes

  • 材料科學(全部)
  • 凝聚態物理學
  • 材料力學
  • 機械工業

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