Cancer cell-specific oligopeptide selected by microfluidic system from a phage display library for ovarian cancer diagnosis

Chih Hung Wang, Chen Hsun Weng, Yu Jui Che, Kuan Wang, Gwo Bin Lee

研究成果: Conference contribution

摘要

Ovarian cancer has been one of the leading causes of death for women. However, it is still very challenging for its early diagnosis. The tedious conventional methods for screening specific biomarkers need at least two weeks or more. It was reported that cancer-specific oligopeptides could be screened from a phage display library. In this study, a new integrated microfluidic chip was developed to perform the entire screening process for specific oligopeptide selection of ovarian cancer cells. The screened oligopeptide was demonstrated to have high affinity with ovarian cancer cells and relatively low capture rate with other types of cancer cells. It is therefore promising to use the screened oligopeptide for isolation of ovarian cancer cells in the near future.

原文English
主出版物標題17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013
發行者Chemical and Biological Microsystems Society
頁面1953-1955
頁數3
ISBN(列印)9781632666246
出版狀態Published - 2013 一月 1
事件17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013 - Freiburg, Germany
持續時間: 2013 十月 272013 十月 31

出版系列

名字17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013
3

Other

Other17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013
國家/地區Germany
城市Freiburg
期間13-10-2713-10-31

All Science Journal Classification (ASJC) codes

  • 生物工程

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