Cancer stem cell molecular markers verified in vivo

Y. S. Kim, A. M. Kaidina, J. H. Chiang, K. N. Yarygin, A. Yu Lupatov

研究成果: Article同行評審

16 引文 斯高帕斯(Scopus)

摘要

This systematic review was aimed at identification of cancer stem cells (CSC) molecular markers, which was validated in experiments on transplantation of tumor subpopulations with different phenotypes to immunodeficient animals. After careful examination of available papers, we selected 97 reports, fully consistent with the objectives of the study. The results of their analysis show that markers commonly used for CSC isolation include: CD133, СD44, ALDH, CD34, CD24, and EpCAM. The review also contains description of molecular features of some CSC markers; it also considers modern approaches to cancer treatment by targeting this population and evaluates perspectives of further development of the CSC theory.

原文English
頁(從 - 到)43-54
頁數12
期刊Biochemistry (Moscow) Supplement Series B: Biomedical Chemistry
11
發行號1
DOIs
出版狀態Published - 2017 1月 1

All Science Journal Classification (ASJC) codes

  • 生物化學
  • 分子醫學
  • 臨床生物化學

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