Case report: Salvage capmatinib therapy in KIF5B-MET fusion-positive lung adenocarcinoma with resistance to telisotuzumab vedotin

Chien Yu Lin, Sheng Huan Wei, Yi Lin Chen, Chung Ta Lee, Shang Yin Wu, Chung Liang Ho, Dean C. Pavlick, Po Lan Su, Chien Chung Lin

研究成果: Article同行評審

摘要

Telisotuzumab vedotin is a MET-targeting antibody–drug conjugate that has demonstrated a good treatment response in patients with EGFR wild-type MET-overexpressing non-squamous non-small cell lung cancer. However, patients have been reported to acquire resistance to this drug, and the subsequent therapy has not been standardized. Here, we present a case of a 56-year-old woman diagnosed with KIF5B-MET fusion-positive non-small cell lung cancer who had a durable response to capmatinib after acquired resistance to telisotuzumab vedotin.

原文English
文章編號919123
期刊Frontiers in Oncology
12
DOIs
出版狀態Published - 2022 8月 11

All Science Journal Classification (ASJC) codes

  • 腫瘤科
  • 癌症研究

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