Cell culture arrangement using ferromagnetic diamond-shaped thin films

Tzong Rong Ger, Chen Yu Huang, Mei Feng Lai

研究成果: Article同行評審

6 引文 斯高帕斯(Scopus)

摘要

Cell patterning has become a prominent technology for tissue engineering. In this research, cell patterning was demonstrated through a diamond-shaped array of magnetic thin films fabricated photolithographically. By utilizing the stray field induced by the magnetic poles at the tips of the thin films, this method can effectively attract magnetically labeled cells and control their position for growing. Magnetic nanoparticles entered the cells via endocytosis, where the amount of particles inside the cells was determined by magnetophoresis experiment. It was observed that magnetically labeled cells can be successfully attracted to the tips of the diamond-shaped magnetic thin film structures, forming a linear cell pattern. We have also found that this structure was capable of collecting and attracting more cells over time. Further proliferation of the patterned cells on the structure suggests that it can be very useful for tissue engineering and biochips.

原文English
文章編號6558997
頁(從 - 到)3453-3455
頁數3
期刊IEEE Transactions on Magnetics
49
發行號7
DOIs
出版狀態Published - 2013 八月 2

All Science Journal Classification (ASJC) codes

  • 電子、光磁材料
  • 電氣與電子工程

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