Cell culture arrays using micron-sized ferromagnetic ring-shaped thin films

Chen Yu Huang, Mei Feng Lai, Tzong Rong Ger, Zung Hang Wei

研究成果: Article同行評審

3 引文 斯高帕斯(Scopus)

摘要

Cell patterning has become an important technology for tissue engineering. In this research, domain walls are formed at the two ends of a ferromagnetic ring thin film after applying a strong external magnetic field, which can effectively attract magnetically labeled cells and control the position for biological cell. Magnetophoresis experiment was conducted to quantify the magnetic nanoparticle inside the cells. A ring-shaped magnetic thin films array was fabricated through photolithography. It is observed that magnetically labeled cells can be successfully attracted to the two ends of the ring-shaped magnetic thin film structure and more cells were attracted and further attached to the structures. The cells are co-cultured with the structure and kept proliferating; therefore, such ring thin film can be an important candidate for in-vitro biomedical chips or tissue engineering.

原文English
文章編號17B309
期刊Journal of Applied Physics
117
發行號17
DOIs
出版狀態Published - 2015 五月 7

All Science Journal Classification (ASJC) codes

  • 物理與天文學 (全部)

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