A sine wave magnetic structure with domain wall (DW) pinning geometry is designed to actively trap magnetically labeled cells. After an initial in-plane magnetic field (Hinitial) is applied and later reduced to zero, and the resultant magnetization became locally aligned. Primary mouse embryonic fibroblasts are magnetically labeled by internalizing magnetic nanoparticles (MNPs). Prussian blue stain and single-cell magnetophoresis are performed to evaluate the internalization of the MNPs. The magnetically labeled cells are then trapped by the stray fields of the head-to-head DWs or the tail-to-tail DWs. The magnetic attraction force is estimated to be 0.2-1.3 pN, while the corresponding magnetic gradient is estimated to be 1.64 to 2.1 T/m.
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