Cells anchored upon a thin organic film with different nano-mechanical properties

Chih Ling Huang, Chia Wei Chang, Jiunn Der Liao, Yi Te Wu, Ming Shaung Ju, Chou Ching K. Lin

研究成果: Article同行評審

6 引文 斯高帕斯(Scopus)

摘要

By applying dynamic contact module and particular measurement of phase angles, harmonic contact stiffness (S) along with the measured displacement (D) of different self-assembled monolayers (SAMs) adsorbed on Au can be distinguished. The relatively ordered and hydrophobic ODT and DDT molecules adsorbed on Au form high contact stiffness, which are presumably unfavorable substrates for a cell to adhere upon. Short-chain MUA molecules adsorbed on Au provides a hydrophilic characteristic with a relatively low contact stiffness, which may significantly promote cell adhesion. It is, therefore, estimated that the behavior of a cell adhered on SAMs/Au is correlated not only with their outermost chemical species but also with a proper dS/dD matrix acting as a cushion.

原文English
頁(從 - 到)301-303
頁數3
期刊Applied Surface Science
255
發行號2
DOIs
出版狀態Published - 2008 十一月 15

All Science Journal Classification (ASJC) codes

  • 化學 (全部)
  • 凝聚態物理學
  • 物理與天文學 (全部)
  • 表面和介面
  • 表面、塗料和薄膜

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