Characterization of Cytochalasins and Steroids from the Ascomycete Daldinia concentrica and Their Cytotoxicity

Hoang Van Trung, Ping Chung Kuo, Nguyen Ngoc Tuan, Nguyen Thi Ngan, Nguyen Quang Trung, Nguyen Tan Thanh, Ha Viet Hai, Doan Lan Phuong, Bach Long Giang, Yue Chiun Li, Tian Shung Wu, Tran Dinh Thang

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2 引文 斯高帕斯(Scopus)

摘要

One new cytochalasin daldinin (1), 2 known cytochalasins 2 and 3, along with 2 steroids 4 and 5, were characterized from the methanol extracts of the fruiting bodies of Daldinia concentrica. The structure of new compound 1 was elucidated using a combination of 1- and 2-dimensional nuclear magnetic resonance spectroscopic and high-resolution electrospray ionization mass spectrometric analyses. In addition, the isolated compounds were examined for their cytotoxicity against several tumor cell lines and the tested compounds demonstrated moderate-to-weak cytotoxicity.

原文English
期刊Natural Product Communications
14
發行號5
DOIs
出版狀態Published - 2019 五月

All Science Journal Classification (ASJC) codes

  • 藥理
  • 藥物發現
  • 植物科學
  • 補充和替代醫學

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