Chemical Constituents from the Fruiting Bodies of Hexagonia apiaria and Their Anti-inflammatory Activity

Tran Dinh Thang; Ping Chung Kuo; Nguyen Thi Bich Ngoc; Tsong Long Hwang; Mei Lin Yang; Shih Huang Ta; E. Jian Lee; Dai Huang Kuo; Nguyen Huy Hung; Nguyen Ngoc Tuan; Tian Shung Wu

doi:10.1021/acs.jnatprod.5b00449

Chemical Constituents from the Fruiting Bodies of Hexagonia apiaria and Their Anti-inflammatory Activity

Tran Dinh Thang, Ping Chung Kuo, Nguyen Thi Bich Ngoc, Tsong Long Hwang, Mei Lin Yang, Shih Huang Ta, E. Jian Lee, Dai Huang Kuo, Nguyen Huy Hung, Nguyen Ngoc Tuan, Tian Shung Wu

研究成果: Article › 同行評審

9 引文斯高帕斯（Scopus）

摘要

A chemical investigation of the fruiting bodies of Hexagonia apiaria resulted in the identification of nine compounds including five new triterpenoids, hexagonins A-E (1-5), along with four known compounds. The purified constituents were examined for their anti-inflammatory activity. Among the tested compounds, hexatenuin A displayed the most significant inhibition of superoxide anion generation and elastase release. These triterpenoids may have potentials as anti-inflammatory agents.

原文	English
頁（從 - 到）	2552-2558
頁數	7
期刊	Journal of Natural Products
卷	78
發行號	11
DOIs	https://doi.org/10.1021/acs.jnatprod.5b00449
出版狀態	Published - 2015 11月 25

All Science Journal Classification (ASJC) codes

分析化學
分子醫學
藥理
藥學科學
藥物發現
補充和替代醫學
有機化學

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10.1021/acs.jnatprod.5b00449

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abstract = "A chemical investigation of the fruiting bodies of Hexagonia apiaria resulted in the identification of nine compounds including five new triterpenoids, hexagonins A-E (1-5), along with four known compounds. The purified constituents were examined for their anti-inflammatory activity. Among the tested compounds, hexatenuin A displayed the most significant inhibition of superoxide anion generation and elastase release. These triterpenoids may have potentials as anti-inflammatory agents.",

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AU - Hwang, Tsong Long

AU - Yang, Mei Lin

AU - Ta, Shih Huang

AU - Lee, E. Jian

AU - Kuo, Dai Huang

AU - Hung, Nguyen Huy

AU - Tuan, Nguyen Ngoc

AU - Wu, Tian Shung

PY - 2015/11/25

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Chemical Constituents from the Fruiting Bodies of Hexagonia apiaria and Their Anti-inflammatory Activity

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