Chip-based microfluidic devices coupled with electrospray ionization-mass spectrometry

Wang Chou Sung, Honest Makamba, Shu Hui Chen

研究成果: Review article

97 引文 斯高帕斯(Scopus)

摘要

We present the current status of the development of microfluidic devices fabricated on different substrates for coupling with electrospray ionization-mass spectrometry (ESI-MS). Until now, much success has been gained in fabricating the ESI chips, which show better performances due to miniaturization when compared with traditional methods. Integration of multiple steps for sample preparation and ESI sample introduction, however, remains a great challenge. This review covers the main technical development of electrospray device that were published from 1997 to 2004. This article does not attempt to be exclusive. Instead, it focuses on the publications that illustrated the breath of the development and applications of microchip devices for MS-based analysis.

原文English
頁(從 - 到)1783-1791
頁數9
期刊Electrophoresis
26
發行號9
DOIs
出版狀態Published - 2005 五月 1

All Science Journal Classification (ASJC) codes

  • Analytical Chemistry
  • Biochemistry
  • Clinical Biochemistry

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