Chronological changes in genetic variance and heritability of anthropometric characteristics among Chinese twin infants

C. J. Chen, M. W. Yu, C. J. Wang, S. L. Tong, M. Tien, T. Y. Lee, H. C. Lue, F. Y. Huang, C. C. Lan, K. H. Yang, H. C. Wang, H. Y. Shih, C. Y. Liu, J. S. Chen

研究成果: Article同行評審

10 引文 斯高帕斯(Scopus)

摘要

In order to examine the chronologic changes in genetic variance and heritability of anthropometric characteristics of Chinese infants in Taiwan, a total of 521 pairs of same-sexed twin neonates given birth in four major general teaching hospitals in Taipei City were studied. Based on the placental pattern and 12 red blood cell antigens, 428 MZ and 93 DZ twin pairs were identified and followed up to the age of one year. There was no significant genetic variance for all anthropometric characteristics adjusted for sex and gestational week before the age of six months. After adjusting for sex and gestational week, a significant genetic variance was observed at the age of six months, with heritability values of 0.5l (weight), 0.63 (head circumference), 0.77 (chest circumference), and 0.53 (arm circumference), as well as at one year, although with considerably lower heritability values. This implies that growth is dynamically determined by both genetic and environmental factors during infancy.

原文English
頁(從 - 到)479-484
頁數6
期刊Acta Geneticae Medicae et Gemellologiae
39
發行號4
DOIs
出版狀態Published - 1990

All Science Journal Classification (ASJC) codes

  • 遺傳學(臨床)

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