Clinical importance of adverse effect in long term use of proton-pump inhibitors

Wei Chun Cheng, Chiung Yu Chen, Xi Zhang Lin

研究成果: Article同行評審

摘要

Proton pump inhibitors are recognized as safe and effective in acid related disorders, and are first choices in these diseases. However, with increased clinical experiences and extended treatment duration in recent years, potential adverse effects and pathophysiological change are reported. We reviewed recent advance in knowledge and mechanism of the adverse events related to proton pump inhibitor use, including hypergastrinemia, bone fracture, infection and drug interaction with Clopidogrel. We aim to provide updated information on clinical concerns and evidences in using proton pump inhibitors.

原文English
頁(從 - 到)304-313
頁數10
期刊Journal of Internal Medicine of Taiwan
22
發行號5
出版狀態Published - 2011 10月 1

All Science Journal Classification (ASJC) codes

  • 內科學

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