Clinical suppression of precocious puberty with cetrorelix after failed treatment with GnRH agoinst in a girl with gonadotrophin-independent precocious puberty

Meng Hsing Wu, Shio Jean Lin, Li Hsiang Wu, Yueh Chin Cheng, Yen Yin Chou, Hsien An Pan

研究成果: Article

5 引文 斯高帕斯(Scopus)

摘要

This report presents the case of a 7-year-old girl with gonadotrophin-independent precocious puberty treated with cetrorelix [gonadotrophin-releasing hormone (GnRH) antagonist] after poor response to GnRH agonist therapy was observed in the endocrinology outpatient clinic. Uterine and ovarian morphology returned to within the normal prepubertal range after GnRH antagonist was injected subcutaneously. Vaginal bleeding stopped completely. The effects of GnRH antagonist treatment were comparable to those of GnRH agonist. The potential advantage of GnRH antagonists would be a clinically significant direct effect on the ovary, if it exists, and GnRH antagonists should be available for use in such children.

原文English
頁(從 - 到)18-21
頁數4
期刊Reproductive BioMedicine Online
11
發行號1
DOIs
出版狀態Published - 2005 七月

All Science Journal Classification (ASJC) codes

  • Reproductive Medicine
  • Obstetrics and Gynaecology
  • Developmental Biology

指紋 深入研究「Clinical suppression of precocious puberty with cetrorelix after failed treatment with GnRH agoinst in a girl with gonadotrophin-independent precocious puberty」主題。共同形成了獨特的指紋。

  • 引用此