Compact and tunable size-based dielectrophoretic flow fractionation

Han Sheng Chuang, Tien Yu Chung, Yun Li

研究成果: Article同行評審

9 引文 斯高帕斯(Scopus)

摘要

A compact and tunable size-based flow fractionation microchip using negative dielectrophoresis (DEP) is presented in this paper. In the microchip, a sample containing a mixture of particles is hydrodynamically focused in a contraction sectionand then sorted by size after flowing over planar interdigitated electrodes. The electrodes and flow chamber were aligned at an angle of 45 to produce effective sorting. 1, 2.5 and 4.8 m polystyrene (PS) particles were successfully separated into three distinct streams in a short distance (1 mm) and collected in different outlet channels. The sorting was subjected to flow rates and electric potential. The experimental sorting efficiencies of 1, 2.5 and 4.8 m particles reached 97.2%, 79.6% and 99.8%, respectively. With the same device, lipid vesicle sorting was demonstrated. 86.9% of vesicles larger than 10 m were effectively extracted from the sample stream. Likewise, sorting of other biological particles can be achieved in the same fashion.

原文English
文章編號125016
期刊Journal of Micromechanics and Microengineering
24
發行號12
DOIs
出版狀態Published - 2014 12月 1

All Science Journal Classification (ASJC) codes

  • 電子、光磁材料
  • 材料力學
  • 機械工業
  • 電氣與電子工程

指紋

深入研究「Compact and tunable size-based dielectrophoretic flow fractionation」主題。共同形成了獨特的指紋。

引用此