Constituents from the root and stem of Aristolochia elegans

Tian-Shung Wu, Yao Lung Tsai, A. G. Damu, Ping-Chung Kuo, Pei Lin Wu

研究成果: Article同行評審

37 引文 斯高帕斯(Scopus)

摘要

Four new tetralones, aristelegone-A (1), aristelegone-B (2), aristelegone-C (3), and aristelegone-D (4); one new isoquinoline, pericampylinone-A (5); four new biphenyl ethers, aristogin-A (6), aristogin-B (7), aristogin-D (8), and aristogin-E (9); three new lignans, aristelegin-A (10), aristelegin-B (11), and aristelegin-C (12); and a new dimer, aristolin (13), have been isolated from the root and stem of Aristolochia elegans. The structures were established on the basis of 1D and 2D NMR and mass spectral data. This is the first report of isoquinolones and biphenyl ethers from this plant which may be representative units for the formation of bisbenzylisoquinoline alkaloids that are common metabolites of Aristolochia species. Aristolin (13) is also the first report of a diterpene linked with an aristolochic acid.

原文English
頁(從 - 到)1522-1525
頁數4
期刊Journal of Natural Products
65
發行號11
DOIs
出版狀態Published - 2002 十一月 1

All Science Journal Classification (ASJC) codes

  • Analytical Chemistry
  • Molecular Medicine
  • Pharmacology
  • Pharmaceutical Science
  • Drug Discovery
  • Complementary and alternative medicine
  • Organic Chemistry

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