Constituents from the stems of Aristolochia manshuriensis

Pei Lin Wu, Gwo Ching Su, Tian-Shung Wu

研究成果: Article同行評審

47 引文 斯高帕斯(Scopus)

摘要

In a continuing search for bioactive compounds from Aristolochia species, 28 compounds, including three new constituents, demethylaristofolin E (1), aristomanoside (2), and dehydrooxoperezinone (3), were isolated from an extract of the stems of Aristolochia manshuriensis. The structures of these compounds were established by extensive 1D and 2D NMR spectral studies. Among these compounds, dehydrooxoperezinone (3) was found to inhibit the replication of HIV, with an EC50 value of 17.5 μg/mL and a therapeutic index of 1.43.

原文English
頁(從 - 到)996-998
頁數3
期刊Journal of Natural Products
66
發行號7
DOIs
出版狀態Published - 2003 7月 1

All Science Journal Classification (ASJC) codes

  • 分析化學
  • 分子醫學
  • 藥理
  • 藥學科學
  • 藥物發現
  • 補充和替代醫學
  • 有機化學

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