Constituents from Vigna vexillata and their anti-inflammatory activity

Yann Lii Leu, Tsong Long Hwang, Ping Chung Kuo, Kun Pei Liou, Bow Shin Huang, Guo Feng Chen

研究成果: Article同行評審

21 引文 斯高帕斯(Scopus)

摘要

The seeds of Vigna genus are important food resources and there have already been many reports regarding their bioactivities. In our preliminary bioassay, the chloroform layer of methanol extracts of V. vexillata demonstrated significant anti-inflammatory bioactivity. Therefore, the present research is aimed to purify and identify the anti-inflammatory principles of V. vexillata. One new sterol (1) and two new isoflavones (2,3) were reported from the natural sources for the first time and their chemical structures were determined by the spectroscopic and mass spectrometric analyses. In addition, 37 known compounds were identified by comparison of their physical and spectroscopic data with those reported in the literature. Among the isolates, daidzein (23), abscisic acid (25), and quercetin (40) displayed the most significant inhibition of superoxide anion generation and elastase release.

原文English
頁(從 - 到)9754-9768
頁數15
期刊International journal of molecular sciences
13
發行號8
DOIs
出版狀態Published - 2012 8月

All Science Journal Classification (ASJC) codes

  • 催化
  • 分子生物學
  • 光譜
  • 電腦科學應用
  • 物理與理論化學
  • 有機化學
  • 無機化學

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