Continuous wave spectroscopy with diffusion theory for quantification of optical properties: Comparison between multi-distance and multi-wavelength data fitting methods

Yung Chi Lin, Zhi Fong Lin, Shoko Nioka, Li Hsin Chen, Sheng-Hao Tseng, Pau-Choo Chung

研究成果: Conference contribution

1 引文 斯高帕斯(Scopus)

摘要

Typically, continuous wave spectroscopy (CWS) can be used to accurately quantify biological tissue optical properties (μa and μs ′) by employing the diffuse reflectance information acquired at multiple source-detector separations (multi-distance). On the other hand, sample optical properties can also be obtained by fitting multi-wavelength light reflectance acquired at a single source detector separation to the diffusion theory equation. To date, multi-wavelength and multidistance methods have not yet been rigorously compared for their accuracy in quantification of the sample optical properties. In this investigation, we compared the accuracy of the two above-mentioned quantifying methods in the optical properties recovery. The liquid phantoms had μa between 0.004 and 0.011 mm−1 and μs ′ between 0.55 and 1.07 mm−1 whose optical properties mimic the human breast. Multi-distance data and multi-wavelength data were fitted to the same diffusion equation for consistency. The difference between benchmark μa and μs ′ and the fitted results, ΔError (ΔE) was used to evaluate the accuracy of the two methods. The results showed that either method yielded Δ E within 15–30 % when values were within certain limits to standard values applicable to μs ′ and μa for human adipose tissue. Both methods showed no significant differences in Δ E values. Our results suggest that both multidistance and multi-wavelength methods can yield similar reasonable optical properties in biological tissue with a proper calibration.

原文English
主出版物標題Oxygen Transport to Tissue XXXVIII
編輯Duane F. Bruley, Qingming Luo, Lin Z. Li, Hua Shi, David K. Harrison, Duane F. Bruley
發行者Springer New York LLC
頁面337-343
頁數7
ISBN(列印)9783319388083
DOIs
出版狀態Published - 2016 一月 1
事件43rd Annual Meeting of the International Society on Oxygen Transport to Tissue, ISOTT 2015 - Wuhan, China
持續時間: 2015 七月 112015 七月 16

出版系列

名字Advances in Experimental Medicine and Biology
923
ISSN(列印)0065-2598
ISSN(電子)2214-8019

Other

Other43rd Annual Meeting of the International Society on Oxygen Transport to Tissue, ISOTT 2015
國家China
城市Wuhan
期間15-07-1115-07-16

    指紋

All Science Journal Classification (ASJC) codes

  • Biochemistry, Genetics and Molecular Biology(all)

引用此

Lin, Y. C., Lin, Z. F., Nioka, S., Chen, L. H., Tseng, S-H., & Chung, P-C. (2016). Continuous wave spectroscopy with diffusion theory for quantification of optical properties: Comparison between multi-distance and multi-wavelength data fitting methods. 於 D. F. Bruley, Q. Luo, L. Z. Li, H. Shi, D. K. Harrison, & D. F. Bruley (編輯), Oxygen Transport to Tissue XXXVIII (頁 337-343). (Advances in Experimental Medicine and Biology; 卷 923). Springer New York LLC. https://doi.org/10.1007/978-3-319-38810-6_44