Correlation of severity of human tick-borne encephalitis virus disease and pathogenicity in mice

Chaitanya Kurhade, Sarah Schreier, Yi Ping Lee, Loreen Zegenhagen, Marika Hjertqvist, Gerhard Dobler, Andrea Kröger, Anna K. Överby

研究成果: Article同行評審

11 引文 斯高帕斯(Scopus)

摘要

We compared 2 tick-borne encephalitis virus strains isolated from 2 different foci that cause different symptoms in tick-borne encephalitis patients, from neurologic to mild gastrointestinal symptoms. We compared neuroinvasiveness, neurovirulence, and proinflammatory cytokine response in mice and found unique differences that contribute to our understanding of pathogenesis.

原文English
頁(從 - 到)1709-1712
頁數4
期刊Emerging infectious diseases
24
發行號9
DOIs
出版狀態Published - 2018 9月

All Science Journal Classification (ASJC) codes

  • 流行病學
  • 微生物學(醫學)
  • 傳染性疾病

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