Cutaneous alternariosis in a renal transplant recipient: A case report and literature review

Chia Chi Hsu, Shen Shin Chang, Po Chang Lee, Sheau Chiou Chao

研究成果: Article同行評審

25 引文 斯高帕斯(Scopus)

摘要

Organ transplant recipients under immunosuppressive therapy have a highly increased risk of acquiring unusual opportunistic infections. Diagnosis of the etiology of infection may be difficult in clinical manifestations, which need further histological and biological investigations. We recently treated a male renal transplant recipient with a cutaneous phaeo-hyphomycosis due to Alternaria species. The diagnosis was based on microscopy and culture of the skin lesions. Treatment with oral itraconazole for 5 weeks was ineffective, then clinical improvement was achieved by combination of amphotericin B wet-packing and systemic anti-fungal therapy with oral voriconazole. Alternaria species are ubiquitous plant-inhabiting sap-robes, which are increasingly associated with opportunistic phaeohyphomycosis in immunocompromised individuals. To the best of our knowledge, this is the second case report noting sporotrichoid pattern as the manifestation of cutaneous alternariosis. In this context, we reviewed recent renal-transplant-related cutaneous alternariosis reported in the English-language literature during 1995 to 2011 to summarize its clinical features and outcomes, and to guide clinicians in the care of kidney transplant patients with cutaneous alternariosis.

原文English
頁(從 - 到)47-57
頁數11
期刊Asian Journal of Surgery
38
發行號1
DOIs
出版狀態Published - 2015

All Science Journal Classification (ASJC) codes

  • 手術

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