Cytomegalovirus infection involving the skin in immunocompromised hosts. A clinicopathologic study

Yu-Yun Lee

研究成果: Review article同行評審

60 引文 斯高帕斯(Scopus)

摘要

Cytomegalovirus (CMV) infection involving the skin in three transplant patients is presented. Patient 1, whose infection apparently was localized only to a cutaneous wound induced by extravasated ionotropic solution, survived. Mixed CMV and Candida infections developed in patient 2 in the cutaneous ulcer. He died of disseminated herpes simplex virus infection in two weeks. Patient 3 had CMV pneumonia and purpuric maculopapular eruption. He died of Pseudomonas sepsis 17 weeks later. Eighteen cases with CMV skin lesions are reported in the English literature. The clinical findings and the outcome of the current and the reported cases are analyzed. All patients were immunocompromised. CMV infection, when detected in the skin, appears to be associated with grave prognosis. Seventeen of 20 patients whose final outcome was recorded died within six months after the onset of CMV skin lesions. The outcome of one case is unknown. The mortality was 85%. The fatal cases had either concurrent disseminated CMV infection or mixed cutaneous or systemic infections. When the infection is localized in the skin wounds, the prognosis seems fairly good. All three such patients survived.

原文English
頁(從 - 到)96-100
頁數5
期刊American Journal of Clinical Pathology
92
發行號1
DOIs
出版狀態Published - 1989 一月 1

All Science Journal Classification (ASJC) codes

  • Pathology and Forensic Medicine

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