Cytotoxic and antiplatelet aggregation principles from Aglaia elliptifolia

Tian Shung Wu, Meei Jen Liou, Chang Sheng Kuoh, Che Ming Teng, Tsuneatsu Nagao, Kuo Hsiung Lee

研究成果: Article同行評審

60 引文 斯高帕斯(Scopus)

摘要

Two related 1H-2,3,3a,8b-tetrahydrocyclopenta[b]benzofurans, aglafolin (1a) and rocaglamide (2), isolated from the stems of Aglaia elliptifolia, showed significant cytotoxicity in six cancer cell lines. Aglafolin (1a) was also found to completely block platelet aggregation caused by arachidonic acid and platelet-activating factor at 100 μM and 2 ng/mL, respectively.

原文English
頁(從 - 到)606-608
頁數3
期刊Journal of Natural Products
60
發行號6
DOIs
出版狀態Published - 1997 六月

All Science Journal Classification (ASJC) codes

  • 分析化學
  • 分子醫學
  • 藥理
  • 藥學科學
  • 藥物發現
  • 補充和替代醫學
  • 有機化學

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