Degradation Behavior of Porous Calcium Phosphates

Chien Wen Wang, Min Yan, Hsien Chang Chang, Shinn Jyh Ding

研究成果: Article同行評審

10 引文 斯高帕斯(Scopus)


Concerning an ideal scaffold, evaluation of many factors, such as porosity, porous size and mechanical properties are needed so as to investigate degradation behavior in addition to chemistry and structure of materials used. In this study, the porous calcium phosphates were made on addition of a pore-former compound (PVA) by sinter processing. Mechanical properties, morphology, and weight change in in vitro testing were assessed. Experimental results indicated macropore sizes as large as hundreds of micrometers were generated and many micropores were also observed in the sintered body. After immersion in Hanks' solution, on the body surface there was a pitting appearance with immersion-induced micropores. The compressive strength of as-sintered bodies decreased steadily with addition of PVA. With increasing immersion time, the compressive strength and modulus of various porous bodies decreased and the weight loss increased. The biomedical uses of the present porous materials might limit to use as bone defect repair.

頁(從 - 到)159-164
期刊Journal of Medical and Biological Engineering
出版狀態Published - 2003 九月 1

All Science Journal Classification (ASJC) codes

  • 生物醫學工程


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