Design and fabrication of 3D-structured contactless capacitive-type detector for capillary electrophoresis microchip

Chia Yen Lee, Che Hsin Lin, Lung Ming Fu

研究成果: Article同行評審

摘要

Using simple and reliable microfabrication techniques, this study develops a capillary electrophoresis (CE) microchip with 3-dimensional-structured (3D-structured) contactless capacitive detector electrodes mounted parallel to the separation channel. The offchannel electrodes are deposited by Au sputtering and patterned using a standard 'lift-off process. A vacuum fusion bonding process is employed to seal the lower substrate containing the microchannels and electrodes to an upper glass cover plate. The variation in the capacitance between the electrodes in the side channels is measured as different samples and ions pass through the detection region of the CE separation channel. Samples of Rhodamine B and a commercial sports drink are mixed in different buffer solutions and successfully separated and detected using the developed device. The 3D-structured contactless capacitive-type detection device has microscale dimensions and provides a valuable contribution to the realization of the lab-on-a-chip concept.

原文English
頁(從 - 到)51-56
頁數6
期刊Journal of Physics: Conference Series
34
發行號1
DOIs
出版狀態Published - 2006 四月 1

All Science Journal Classification (ASJC) codes

  • 物理與天文學 (全部)

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