With the development of Internet technology and computing costs continue to decline, the realization of being the dream of digital home life. In this paper, we will explore Open Service Gateway initiative (OSGi) technology to develop a transferable framework to support a cross-platform environment of health-care service Intelligent Home Health-Care Box platform to achieve the following objectives: (1) To develop remote physiological signal measurements (2) To take advantage of OSGi (Open Service Gateway initiative) to construct a transferable framework for embedded computing. (3) To reduce the program size in an embedded system and upgrade the performance in run time stage. In this constructed environment, home user can demand services prompted by a service-discovery mechanism and interact with health-care devices through network. In other words, networking, intelligence and multimedia are the guidelines to investigate and develop the residential information system who will serve people at home in a friendly manner and improve the quality of home living.