Design and synthesis of new cationic water-soluble pyrene containing dendrons for DNA sensory applications

Ching Yi Chen, Yumiko Ito, Yu Cheng Chiu, Wen Chung Wu, Tomoya Higashihara, Mitsuru Ueda, Wen Chang Chen

研究成果: Article同行評審

7 引文 斯高帕斯(Scopus)

摘要

A series of new water-soluble cationic pyrene-dendron derivatives, G1, G2, and G3, was successfully synthesized and characterized. These new dendrons were designed with the quaternized amino moieties at the periphery of the dendrons for DNA detection and functionalized with pyrene as a fluorescent probe. The electrostatic interactions between the plasmid DNA (pDNA) and cationic charged dendrons in an aqueous solution resulted in a change in the photophysical properties of pyrene, which could be shown in the UV-vis and fluorescence spectra. Pyrene dendrons showed a high and rapid fluorescence response upon the addition of pDNA, which was strongly dependent on the size and hydrophobicity of the dendrons.

原文English
頁(從 - 到)297-305
頁數9
期刊Journal of Polymer Science, Part A: Polymer Chemistry
50
發行號2
DOIs
出版狀態Published - 2012 一月 15

All Science Journal Classification (ASJC) codes

  • 聚合物和塑料
  • 有機化學
  • 材料化學

指紋

深入研究「Design and synthesis of new cationic water-soluble pyrene containing dendrons for DNA sensory applications」主題。共同形成了獨特的指紋。

引用此