Developing an intervention strategy to reduce phthalate exposure in Taiwanese girls

Chung Yu Chen, Yen Yin Chou, Shio Jean Lin, Ching Chang Lee

研究成果: Article同行評審

31 引文 斯高帕斯(Scopus)

摘要

Children in Taiwan seem to be exposed to higher concentrations of phthalates than do children in Western countries. We developed intervention strategies to reduce the exposure of phthalates in Taiwanese girls. Thirty girls 4-13. years old who had been exposed to high levels of phthalates were selected from prior studies. To reduce their phthalate-exposure sources, we developed seven intervention strategies: handwashing, not using plastic containers, not eating food with a plastic bag/plastic-wrap cover, not microwaving food, not taking nutrition supplements, and reducing use of cosmetics/personal care products. Pre- and post-intervention urine samples were collected during a one-week study. HPLC-MS/MS was used to analyze urinary phthalate metabolites. The dominant urinary phthalate metabolite was mono-n-butyl phthalate (MBP), followed by mono-(2-ethyl-5-hydroxyhexyl) phthalate (MEHHP), and mono-(2-ethyl-5-carboxypentyl) phthalate (MECPP). Post-intervention concentrations of eight urinary phthalate metabolites were significantly lower. Girls in the high-frequency handwashing group had significantly lower urinary MBP (p= 0.009) and mono-methyl phthalate (MMP) (p= 0.07) than did girls in the low-frequency handwashing group. Girls who drank fewer beverages from plastic cups had significantly lower urinary MBP (p= 0.016), MEHHP (p= 0.038), and MECPP (p= 0.012). Girls who used less shampoo and shower gel also had marginally significantly lower urinary MBP (p= 0.06) and mono-ethyl phthalate (MEP) (p= 0.06). The intervention strategies that we set up in this study were effective for reducing exposure to phthalates in children. Handwashing and drinking fewer beverages from plastic cups were the most effective strategies for reducing phthalate metabolites in urine, especially MBP and di(2-ethylhexyl) phthalate (DEHP) metabolites. Education and voluntary self-restraint were useful for reducing the body burden of phthalates.

原文English
頁(從 - 到)125-131
頁數7
期刊Science of the Total Environment
517
DOIs
出版狀態Published - 2015 6月 1

All Science Journal Classification (ASJC) codes

  • 環境工程
  • 環境化學
  • 廢物管理和處置
  • 污染

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