Development of specific aptamers with different histological classified ovarian cancer cells by utilizing on-chip OvCa cell-selex

Lien Yu Hung, Chih Hung Wang, Keng-Fu Hsu, Cheng-Yang Chou, Gwo Bin Lee

研究成果: Conference contribution

摘要

Ovarian cancer is the second most common type of gynecological cancers. Comparing with the worst gynecological cancer, cervical cancer, the prognostication of ovarian cancer is relatively poor. It is challenging to diagnose it in the early stage where proper treatments are most effective. In order to achieve early detection of ovarian cancer, biomarkers with high specificity and affinity is therefore important. In this study, an integrated microfluidic system was developed for the multiple-cell-line and high-throughput screening of OvCa cell-SELEX automatically. An aptamer specific to ovarian cancer cells were successfully screened.

原文English
主出版物標題17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013
發行者Chemical and Biological Microsystems Society
頁面368-370
頁數3
1
ISBN(列印)9781632666246
出版狀態Published - 2013
事件17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013 - Freiburg, Germany
持續時間: 2013 十月 272013 十月 31

Other

Other17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013
國家/地區Germany
城市Freiburg
期間13-10-2713-10-31

All Science Journal Classification (ASJC) codes

  • 生物工程

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